Figure 2. Collection of interstitial fluid (IF) from tissues.
A IF was collected from different amounts of 4T1 breast tumor tissue. Correlation between the tumor tissue weight and the volume of IF collected is shown. B Removal of contaminating cells from IF. Cell numbers in IF were determined after centrifugation as indicated. C 10 μg of protein from lymph node tissue extracts (LN) or from IF were analyzed by western blotting with anti-actin antibody (lower panel) and stained with Ponceau S to visualize proteins (upper panel). Densitometry of the blot was assessed using Image J software, and the relative level of actin was normalized with equal protein amount of LN and IF.
