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NOX-1 and HuR participate in cell migration induced by AngII+IL-1β. (A) Transwell assay performed in rat VSMC unstimulated and stimulated with AngII, IL-1β or AngII+IL-1β for 24 h. (B) Effect of ML171 and MS-444 on cell migration induced by AngII+IL-1β. Effect of NOX-1 (C) or HuR (D) siRNA on cell migration induced by AngII+IL-1β. Data are expressed as mean±SEM. *P<0.05, **P<0.01 vs Control. †P<0.05 vs AngII or IL-1β; ‡P<0.05, ‡‡P<0.01 vs AngII+IL-1β. n=3–4.
