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. Author manuscript; available in PMC: 2016 Jul 17.
Published in final edited form as: Cell Rep. 2016 Jun 23;16(2):520–530. doi: 10.1016/j.celrep.2016.05.092

Table 1.

A human clinical trial of PR – physical parameters.

Protein
restricted
within-
group p
Control within-
group p
Among-
group p
Age (yrs) 52.46 ± 6.76 53.00 ± 7.71 0.82
BMI (kg/m2)
  Baseline 30.66 ± 5.43 30.15 ± 5.84
  Follow-up 29.90 ± 5.32 30.18 ± 5.67
Δ BMI −0.76 ± 0.75 < 0.0001 0.03 ± 0.51 0.81 0.001
Weight (kg)
  Baseline 101.46 ± 18.75 93.17 ± 17.25
  Follow-up 98.84 ± 18.61 92.96 ± 16.87
Δ Weight −2.62 ± 2.18 < 0.0001 −0.21 ± 1.36 0.52 0.001
Fat mass (kg)
  Baseline 33.24 ± 11.91 31.07 ± 11.83
  Follow-up 31.86 ± 11.09 30.72 ± 11.45
Δ Fat mass −1.37 ± 1.55 0.001 −0.36 ± 1.02 0.15 0.02

Humans were randomly assigned to a 7-9% protein restricted or control diet group (19 male subjects per group), and physical parameters were assessed at baseline and at a follow-up visit 43 ± 11 days later. Change (Δ) represents the difference between the baseline and follow-up visit. Changes between and within the PR and control groups were tested with analysis of covariance and paired t-tests. Statistical tests were two-tailed, with significance accepted at p < 0.05. Errors represent standard deviation.