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Post-infarction arrhythmogenesis. (A) High-resolution MRI-based model of the infarcted rabbit ventricle with fibroblasts incorporated in the zone of infarct. (B) Coupling of fibroblasts to myocytes (80% in the scar and 10% in the PZ) results in arrhythmia. Red arrow indicates the location of the premature activation. (Modified and reprinted with permission from (McDowell et al., 2011))
