Table 4.

Association of gastric histopathology scores with additive and dominant models of GATA5 SNPs in the Replication cohort

Independent variables	Minor allele	MAF	n	β	95 % CI	p value
Add rs6061243	G	0.460	149	–0.24	(–0.45, –0.024)	0.029
Region of origin				0.11	(–0.29, 0.50)	0.6
vacA s2				–0.63	(–1.082, –0.18)	0.007
Add rs6587239	T	0.457	150	–0.26	(–0.47, –0.039)	0.021
Region of origin				0.20	(–0.20, 0.59)	0.328
vacA s2				–0.62	(–1.08, –0.16)	0.009
Dom rs6061243	G	0.460	149	–0.30	(–0.62, 0.032)	0.076
Region of origin				0.12	(–0.28, 0.52)	0.564
vacA s2				–0.63	(–1.08, –0.17)	0.007
Dom rs6587239	T	0.457	150	–0.33	(–0.66, 0.00)	0.050
Region of origin				0.22	(–0.18, 0.62)	0.276
vacA s2				–0.62	(–1.08, –0.16)	0.009

Analyses were adjusted for region of origin and the H. pylori virulence factor vacA s

Add additive model, Dom dominant model, MAF minor allele frequency