FIGURE 6.

Alaskan lowbush cranberry treatments increase occurrence of process branching in aging posterior touch receptor neurons. Animals from control and lifespan-extending lowbush cranberry treatments (50 and 400 μg/mL) were imaged for touch receptor neuron aberrations at days 5, 7, 9, and 11 of adulthood. Mean number of total aberrations (A) and branches observed on the dentrite/axon per posterior lateral touch receptor (PLM) neuron (B) are shown. Representative images of posterior neuron processes with no aberrations (C,D), with one process branch (E), and with multiple process branching events (F) are also shown. Bars represent mean ± standard error of the mean. Asterisks (p < 0.05) and hashtags (p < 0.085) denote significance from age-matched control. Nposterior cells = 48–73 per bar. In all images, the anterior end of the animal is to the right and posterior lateral touch receptor (PLM) neurons are shown. All images were collected at 20× magnification and were cropped to the same scale (no other image processing was performed). White scale bars are 10 μm.