Table 2.
Alterations in gene expression in healthy gingival tissues related to gene functional categories.
| Gene functions | Total genes | Altered gene expression |
||||||
|---|---|---|---|---|---|---|---|---|
| Total | Young | Adolescent | Aged | |||||
| ↑ or ↓ | ↑ | ↓ | ↑ | ↓ | ↑ | ↓ | ||
| Antigen-dependent activation | 38 | 10 | 0 | 6 | 1 | 3 | 8 | 0 |
| B cell activation | 18 | 4 | 0 | 1 | 0 | 0 | 3 | 3 |
| B cell proliferation | 33 | 6 | 0 | 2 | 0 | 2 | 5 | 0 |
| Differentiation/maturation | 58 | 22 | 1 | 8 | 4 | 9 | 18 | 1 |
| Plasmacyte | 25 | 2 | 0 | 1 | 0 | 2 | 1 | 0 |
| Multiple functions | 17 | 3 | 0 | 2 | 0 | 2 | 1 | 0 |
↑ or ↓ denotes gene expression that was up- or downregulated compared with healthy adult tissues.