Table I.
Animals | HR [bpm] | SABP [mm Hg] | MABP [mm Hg] | DABP [mm Hg] |
---|---|---|---|---|
Sham | 358.1 ±24.6 | 99.2 ±3.2 | 93.3 ±4.9 | 87.8 ±6.0 |
MCT + Vehicle | 402.6 ±27.8 | 101.1 ±5.7 | 95.9 ±5.7 | 90.9 ±5.6 |
Fasudil | 398.1 ±44.9 | 95.0 ±8.3# | 93.0 ±8.1# | 89.3 ±8.1 |
Fasudil + rosuvastatin | 374.0 ±85.4 | 87.5 ±1.6*,† | 85.1 ±2.8*,† | 83.5 ±2.8* |
Data expressed as mean ± SD
p < 0.05 vs. Sham
p < 0.05 vs. MCT + Vehicle
p < 0.05 vs. combination group