Table 1. Observed and expected numbers of controls and mutant Mcl1 EC by age.
Control | Mcl1EC/+ | Mcl1EC/EC | TOTAL | |
---|---|---|---|---|
E10.5a | ||||
Observed | 12 | 8 | 5 | 25 |
Expected | 15 | 6 | 4 | 25 |
E14.5b | ||||
Observed | 60 | 35 | 18 (2)c | 110 |
Expected | 55 | 27.5 | 27.5 | 110 |
Weaningd | ||||
Observed | 96 | 37 | 3e | 136 |
Expected | 85 | 34 | 17 | 136 |
Intercrosses between Mcl1fl/+ or Mcl1fl/fl females and Mcl1fl/+;Tie2-CreT/+ males.
Intercrosses between Mcl1fl/fl females and Mcl1fl/+;Tie2-CreT/+ males.
Number in parenthesis denotes embryos that were phenotypically normal.
Intercrosses between Mcl1fl/+ females and Mcl1fl/+;Tie2-CreT/+ males.
P=0.001, χ2-test