Table 2.
Baseline assessment of coinfected patients.
| Test | Comment | |
|---|---|---|
| Viral hepatitis screens | HCV antibody | |
| Quantitative HCV RNA | ||
| HCV genotype | ||
| Hepatitis B surface antigen | Chronic HBV infection | |
| Hepatitis B surface antibody | Immunity to HBV | |
| Hepatitis B core antibody | ||
| Hepatitis A IgG | If negative, indicates need for HAV vaccine | |
|
| ||
| Liver-related | Complete blood count | Thrombocytopenia may indicate advanced liver disease |
| ALT, AST | ||
| ALP, GGT | ||
| Albumin, INR, and total bilirubin | Abnormalities suggest advanced liver disease | |
| Ultrasound | ||
| Fibroscan | ||
|
| ||
| Screens for other chronic conditions of liver disease | Alpha-1-antitrypsin | Alpha-1 antitrypsin deficiency |
| Antinuclear antibody, anti-smooth muscle antibody | Autoimmune hepatitis | |
| Anti-mitochondrial antibody | Primary biliary cholangitis | |
| Ceruloplasmin | Wilson's disease | |
| Iron saturation | Hemochromatosis | |
| Lipid Profile | Fatty liver disease | |
| TSH | Autoimmune thyroiditis | |
| Immunoglobulins A, G, and M | Autoimmune hepatitis, primary biliary cholangitis, and alcoholic liver disease | |