Table 6. Distribution of binary groups, representing allele positivity, in patients with MRDFC-positive and MRDFC-negative status.
| Time point | Gene Polymorphism | Allele positivity | MRDFC status |
OR | 95% CI | P | |||
|---|---|---|---|---|---|---|---|---|---|
| Negative | Positive | ||||||||
| Day 15 | VDR | AA + AG | 9 | 74 | 2.26 | 0.86–5.91 | 0.132 | ||
| GG | 11 | 40 | |||||||
| rs1544410 | GG + AG | 20 | 94 | N/A | N/A | 0.080 | |||
| AA | 0 | 20 | |||||||
| Day 33 | IL15 | AA + AC | 18 | 11 | 2.91 | 1.17–7.27 | 0.0241,2 | ||
| CC | 81 | 17 | |||||||
| rs10519613 | CC + AC | 98 | 28 | N/A | N/A | 1.0 | |||
| AA | 1 | 0 | |||||||
| RFC | AA + AG | 61 | 21 | 1.82 | 0.71–4.69 | 0.264 | |||
| GG | 37 | 7 | |||||||
| rs1051266 | GG + AG | 79 | 17 | 0.37 | 0.15–0.92 | 0.0431,2 | |||
| AA | 19 | 11 | |||||||
| Week 12 | RFC | AA + AG | 71 | 4 | N/A | N/A | 0.307 | ||
| GG | 34 | 0 | |||||||
| rs1051266 | GG + AG | 80 | 0 | N/A | N/A | 0.0041,2,3 | |||
| AA | 25 | 4 | |||||||
Negative/Positive, number of patients with MRD-negative/MRD-positive results, within each of the binary groups representing allele positivity; OR, odds ratio; 95% CI, 95% confidence interval. 1Results statistically significant at α = 0.05 (Pearson χ2 test or, if expected frequencies <5, 2-sided Fisher’s exact probability test). 2,3Results significant after Benjamini-Hochberg procedure at false discovery rate, 2FDR = 0.1 and also at 3FDR = 0.05.