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. 2016 Jul 18;6:29427. doi: 10.1038/srep29427

Table 6. Distribution of binary groups, representing allele positivity, in patients with MRDFC-positive and MRDFC-negative status.

Time point Gene Polymorphism Allele positivity MRDFC status
OR 95% CI P    
Negative Positive    
Day 15 VDR AA + AG 9 74 2.26 0.86–5.91 0.132    
  GG 11 40          
rs1544410 GG + AG 20 94 N/A N/A 0.080    
  AA 0 20          
Day 33 IL15 AA + AC 18 11 2.91 1.17–7.27 0.0241,2    
  CC 81 17          
rs10519613 CC + AC 98 28 N/A N/A 1.0    
  AA 1 0          
RFC AA + AG 61 21 1.82 0.71–4.69 0.264    
  GG 37 7          
rs1051266 GG + AG 79 17 0.37 0.15–0.92 0.0431,2    
  AA 19 11          
Week 12 RFC AA + AG 71 4 N/A N/A 0.307    
  GG 34 0          
rs1051266 GG + AG 80 0 N/A N/A 0.0041,2,3    
  AA 25 4          

Negative/Positive, number of patients with MRD-negative/MRD-positive results, within each of the binary groups representing allele positivity; OR, odds ratio; 95% CI, 95% confidence interval. 1Results statistically significant at α = 0.05 (Pearson χ2 test or, if expected frequencies <5, 2-sided Fisher’s exact probability test). 2,3Results significant after Benjamini-Hochberg procedure at false discovery rate, 2FDR = 0.1 and also at 3FDR = 0.05.