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(A) Visualization of the RDN topology of biomedical concepts of different data types (numeric, ordinal, nominal, and binary, represented in node shapes); association polarity (positive, negative, or not applicable); and the HER2 module (A) and ER module (B). (B) Characters of the HER2 and ER modules: pivot concepts, phenotypic features, molecular underpinnings, and most common treatments.
