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. 2016 Jul 18;6:29903. doi: 10.1038/srep29903

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Copyright © 2016, Macmillan Publishers Limited

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Vero cells were infected with an MOI of 5 and the supernatant was harvested at several time points to show viral replication behaviour as function of time. The TK-mutated strains R41H, G61A, P84L, R106H, A118V, L139V, K219T, S276R, L298R, S345P, and V348I (dotted lines) were compared with their EGFP-tagged counterparts (solid lines). The growth kinetic of the HSV1(17⁺)Lox strain is depicted separately (dashed line). The data were plotted as a mean and SD of triplicates.