Table 1.
Clinical characteristics of patients with sarcoidosis with parotid gland involvement
Patient No. | Age at diagnosis (years) |
Sex and race | Presentations of parotid gland disease | First presentation of sarcoidosis | Biopsy | Chest imaging | Other extra-thoracic involvement | ACE level | Serum Calcium | Treatment | Response to treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 50 | Male/White | Painless bilateral parotid gland swelling | Yes | Performed; non-caseating granuloma | Bilateral hilar adenopathy and pulmonary infiltration | None | Normal | Normal | Oral prednisone | Parotid gland regressed to normal size |
2 | 21 | Male/White | Painless unilateral parotid gland swelling and xerostomia | No | Performed; non-specific inflammation | Bilateral hilar adenopathy | Eyes and liver | Normal | Normal | Oral prednisone | Parotid gland regressed to normal size |
3 | 48 | Female/White | Painless unilateral parotid gland swelling | Yes | Not performed | Bilateral hilar adenopathy | Erythema nodosum and liver | Elevated | Normal | Oral prednisone | Parotid gland regressed to normal size |
4 | 38 | Male/Black | Painless unilateral parotid gland swelling | No | Not performed | Bilateral hilar adenopathy and pulmonary infiltration | Skin rash and lacrimal gland | Elevated | Normal | Oral prednisone | Parotid gland regressed to normal size |
5 | 55 | Female/White | Painless unilateral parotid gland swelling and numbness over the swollen area | Yes | Performed; non-caseating granuloma | Bilateral hilar adenopathy | None | Normal | Normal | Oral prednisone | Parotid gland regressed to normal size. Relapse once, also responded to prednisone |
6 | 44 | Male/White | Painless unilateral parotid gland swelling | No | Performed; non-caseating granuloma | Normal | None | Elevated | Normal | NSAIDs and oral prednisone | Did not respond to NSAIDs but parotid gland regressed to normal size after switching to prednisone |
7 | 55 | Female/White | Painless unilateral parotid gland swelling | Yes | Performed; non-caseating granuloma | Fibrosis in lung parenchyma with minimal Bilateral hilar adenopathy | Skin rash | Not performed | Not performed | Oral prednisone | Parotid gland regressed to normal size |
ACE = angiotensin converting enzyme; NSAIDs = non-steroidal anti-inflammatory drug