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. 2016 Jul 16;22:816–826.

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Copyright © 2016 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Transduction of rat retina with tm-scAAV2-GFP. The upper row shows the green fluorescent protein (GFP) expression pattern for a healthy retina, and the bottom row shows the GFP expression pattern for the ischemia/reperfusion (I/R) injured retina. After injection of mutant (triple Y-F) self-complementary adeno-associated virus type 2 vector encoding green fluorescent protein (tm-scAAV2-GFP) into the rat vitreous cavity, GFP expression was detected in the ganglion cell layer (GCL), Müller, and inner nuclear layer (INL) cells. Scale bar, 50 μm.