Table 2.
Inhibitory effect of 7-methylguanine and related compounds on PARP-1 and PARP-2.
| IC50 (μM) | ||
|---|---|---|
| PARP-1 | PARP-2 | |
| 7-methylguanine | 150 | 50 |
| 7-methylxanthine | 800 | 160 |
| 7-methylhypoxanthine | 780 | 620 |
| 7-ethylguanine | 230 | 90 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.