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| CL (mL/min/kg) | Vss (L/kg) | t1/2 (h) | F (%) | |
|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | |
| Mouse | 5.33 ± 0.81 | 0.57 ± 0.10 | 2.44 ± 0.13 | 96 ± 19 |
| Rat | 5.35 ± 0.65 | 0.70 ± 0.05 | 2.77 ± 0.14 | 84 ± 3 |
| Dog | 0.67 ± 0.14 | 0.25 ± 0.06 | 8.86 ± 1.76 | 72 ± 22 |
The compound was administered as a solution in 20% PEG300/3% ETPGS for mouse and rat or 25% PEG300/5% Solutol for dog.
