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. 2016 Jun 1;7(7):666–670. doi: 10.1021/acsmedchemlett.6b00145

Table 2. Exploration of the Cyclic Group at the 5-Position.

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a

The estimated coefficients of variation for the EC50, S0.5, and Vmax are 30% (n = 383), 17% (n = 297), and 4% (n = 329), respectively, based on the performance of a reference compound. Also, human recombinant GK was used in all the assays