Table 1. Patient characteristics and observed pathological complete response.
| Characteristics | Number of patients | Number of pCR (%) | P value | P value* |
|---|---|---|---|---|
| Age | 0.534 | 0.842 | ||
| <40 | 58 | 23 (39.6) | ||
| 40–59 | 175 | 58 (33.1) | ||
| 60+ | 47 | 14 (29.8) | ||
| Menopausal status | 0.779 | 0.948 | ||
| Pre | 150 | 52 (34.7) | ||
| Post | 130 | 43 (33.1) | ||
| Tumor size at baseline | 0.043 | 0.223 | ||
| T2 | 136 | 56 (41.2) | ||
| T3 | 97 | 27 (27.8) | ||
| T4 | 47 | 12 (25.5) | ||
| Node status at baseline | 0.986 | 0.697 | ||
| − | 47 | 16 (34.0) | ||
| + | 233 | 79 (33.9) | ||
| Cancer stage at baseline | 0.040 | 0.359 | ||
| II | 153 | 60 (39.2) | ||
| III | 127 | 35 (27.6) | ||
| Histology at baseline | 0.102 | 0.433 | ||
| Invasive ductal carcinoma | 205 | 77 (37.6) | ||
| Invasive (mixed) carcinoma | 60 | 14 (23.3) | ||
| Others | 15 | 4 (26.7) | ||
| Ki-67 expression at baseline | ||||
| Category | <0.001 | <0.001 | ||
| Low (<20%) | 99 | 14 (14.1) | ||
| Median (20%–50%) | 85 | 25 (29.4) | ||
| High (50%+) | 96 | 56 (58.3) | ||
| Linear | <0.001 | <0.001 | ||
| CK5/6 | 0.560 | 0.574 | ||
| − | 120 | 43 (35.8) | ||
| + | 160 | 52 (32.5) | ||
| EGFR | 0.168 | 0.372 | ||
| − | 131 | 39 (29.8) | ||
| + | 149 | 56 (37.6) | ||
Abbreviations: pCR, pathological complete response; CK, cytokeratin; EGFR, epidermal growth factor receptor.
*P value of the multivariate logistic regression.