Table 1.
Baseline characteristics of users of non-insulin antidiabetic agents. Values are numbers (percentages) unless stated otherwise
| Characteristics | Users of non-insulin antidiabetes agents (n=120 803) | |
|---|---|---|
| Mean (SD) follow-up time | 3.65 (2.4) | |
| Women | 57 065 (47.2) | |
| Mean (SD) age (years) | 67.4 (16.0) | |
| Age group (years): | ||
| 18-29 | 2127 (1.8) | |
| 30-39 | 4014 (3.3) | |
| 40-49 | 10 157 (8.4) | |
| 50-59 | 19 319 (16.0) | |
| 60-69 | 27 815 (23.0) | |
| 70-79 | 29 042 (24.0) | |
| ≥80 | 28 329 (23.5) | |
| Most recent renal function in past year (mL/min/1.73 m2): | ||
| <30 | 734 (0.6) | |
| 30-59 | 19 070 (15.8) | |
| ≥60 | 60 025 (49.7) | |
| Unknown | 40 974 (33.9) | |
| Mean (SD) haemoglobin A1c (%) | 8.32 (1.86) | |
| Unknown | 57 850 (47.9) | |
| Smoking status: | ||
| Current smoker | 22 007 (18.2) | |
| Former smoker | 49 598 (41.1) | |
| Never smoker | 48 328 (40.0) | |
| Unknown | 870 (0.7) | |
| Alcohol use: | ||
| Yes | 77 880 (64.5) | |
| No | 35 427 (29.3) | |
| Unknown | 7496 (6.2) | |
| Body mass index: | ||
| <20.0 | 1670 (1.4) | |
| 20.0-24.9 | 14 759 (12.2) | |
| 25.0-29.9 | 36 907 (30.6) | |
| ≥30.0 | 63 770 (52.8) | |
| Unknown | 3697 (3.1) | |
| History of disease: | ||
| Asthma or COPD | 18 698 (15.5) | |
| Cardiovascular disease | 18 863 (15.6) | |
| Chronic liver disease | 321 (0.3) | |
| Cognitive impairment or dementia | 1767 (1.5) | |
| Drug use in past six months: | ||
| Thiazide diuretics | 20 689 (17.1) | |
| RAAS inhibitors | 43 611 (36.1) | |
| Loop diuretics | 10 918 (9.0) | |
| β blockers | 20 843 (17.3) | |
| Calcium channel blockers | 23 963 (19.8) | |
| Typical antipsychotics | 1079 (0.9) | |
| Atypical antipsychotics | 1693 (1.4) | |
| SSRIs | 9159 (7.6) | |
| SNRIs | 1491 (1.2) | |
| Tricyclic antidepressants | 7276 (6.0) | |
| Monoamine oxidase inhibitors | 22 (0.02) | |
| NSAIDs | 15 471 (12.8) | |
| Statins | 50 925 (42.2) | |
| Corticosteroids (systemic) | 6185 (5.1) | |
| Oral anticoagulants | 4620 (3.8) | |
| Trimethoprim | 4838 (4.0) | |
COPD=chronic obstructive pulmonary disease; NSAIDs=non-steroidal anti-inflammatory drugs; RAAS=renin-angiotensin-aldosterone system; SSRIs=selective serotonin reuptake inhibitors; SNRIs=serotonin-norepinephrine reuptake inhibitors.