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. 2016 Jun 29;148(4):326–338. doi: 10.1111/imm.12611

Figure 2.

Figure 2

Mice whose microRNA (miR) 223 was globally deficient are resistant to experimental autoimmune encephalomyelitis (EAE) induction. (a) Clinical scores of EAE and (b) motor function (30‐second maximum recorded) were determined at various times after MOG immunization. (c) Histological analysis of spinal cord sections 22 days after MOG immunization. Each panel shows the representative image of three mice analysed per group. Original magnification ×4 (larger) and ×20 (inset). Similar results were obtained in two independent experiments. Data represent the mean ± SEM (*P < 0·05, ***P < 0·001).