Table 1.
Distribution and genotypes of couples with and without different sickle cell disorders
| No. of Couples (N) | Genotypes of Couples (Diagnosis) | Interpretation of Genotypes |
|---|---|---|
| 65 | AA/AS | Normal husband and sickle cell trait wife or normal wife and sickle cell trait husband |
| 18 | AA/SS | Normal husband and sickle cell disease wife or vice versa |
| 72 | AS/AS | Both husband and wife are carrier for sickle cell disease |
| 9 | AS/SS | One partner is carrier for sickle cell disease and other partner is suffering from sickle cell disease |
| 15 | AS/β-Thalassemia Trait | One partner being carrier for sickle cell disease and the counterpart is β-thalassemia trait (or carrier of thalassemia major) |
| 4 | AS/Sickle cell- β-Thalassemia | One partner being carrier of sickle cell disease and the other partner is sickle cell-β-thalassemia (having compound disease, i.e. sickle cell disease and β-thalassemia) |
| 183 | Sickle Cell Disorders (All above combined) | All the above diagnostic categories (genotypes) combined together except the normal controls |
| 200 | AA/AA (Normal) | Normal husband and normal wife (control) |