Table 3.
Post-bronchodilator FEV1 percent-predicted | beta (95% CI) | p-value | |
---|---|---|---|
ET-1* | −0.20 (−0.30 – −0.11) | <0.001 | |
Pack-years smoked** | −0.01 (−0.03 – −0.002) | 0.02 | |
Time (per year) | −0.03 (−0.04 – −0.02) | <0.001 | |
Interaction term between ET-1 and time | ---- | 0.16 | |
DLCO percent-predicted | beta (95% CI) | p-value | |
sCD163* | −0.08 (−0.16 – −0.001) | 0.047 | |
Pack-years smoked** | −0.02 (−0.03 – −0.005) | 0.005 | |
Time (per year) | 0.02 (0.006 – 0.04) | 0.005 | |
Interaction term between sCD163 and time | ---- | 0.90 | |
DLCO percent-predicted | beta (95% CI) | p-value | |
ET-1* | −0.10 (−0.20 – −0.006) | 0.04 | |
Pack-years smoked** | −0.01 (−0.03 – −0.001) | 0.04 | |
Time (per year) | 0.02 (0.007 – 0.04) | 0.005 | |
Interaction term between ET-1 and time | ---- | 0.30 |
CI: confidence interval, DLCO: diffusing capacity for carbon monoxide, ET-1: endothelin-1, FEV1: forced expiratory volume in one second
Log transformation
Square-root transformation