Table 4.

Blood Chemistry

	Reference ranges
Test (Unit)	Min	Max	Placebo week 0	Placebo week 2	P* placebo (0–2 weeks)	ACE week 0	ACE week 2	P* ACE (0–2 weeks)	P** placebo ACE
Sodium (mmol/L)	135.00	145.00	138.19 ± 1.16	137.73 ± 2.11	.411	137 ± 2.01	137.39 ± 1.76	.526	.291
Potassium (mmol/L)	3.50	5.10	4.21 ± 0.25	4.2 ± 0.22	.921	4.21 ± 0.1	4.08 ± 0.2	.027	.219
Chloride (mmol/L)	101.00	111.00	105.56 ± 1.34	105.64 ± 1.87	.880	105.54 ± 3.02	105.29 ± 1.65	.735	.757
CO2 (mmol/L)	22.00	32.00	25.68 ± 1.14	24.86 ± 2.23	.173	24.85 ± 2.32	25.74 ± 2.34	.135	.038
Calcium (mg/dL)	8.60	10.30	9.28 ± 0.38	9.26 ± 0.33	.882	9.1 ± 0.27	9.02 ± 0.26	.384	.626
BUN (mg/dL)	6.00	20.00	12.58 ± 3.34	12.08 ± 2.71	.663	14.58 ± 3.58	13.08 ± 3.26	.160	.422
Creatinine (mg/dL)	0.60	1.30	0.83 ± 0.14	0.81 ± 0.16	.391	0.78 ± 0.19	0.77 ± 0.14	.877	.375
BUN/Crea ratio	12.00	20.00	15.31 ± 3.83	15.65 ± 4.97	.829	19.68 ± 7.05	17.38 ± 5.07	.169	.296
Glucose (mg/dL)	74.00	106.00	83.5 ± 11.73	82.08 ± 8.61	.507	85.25 ± 5.99	84.25 ± 8.5	.661	.983
Total protein (g/dL)	6.50	8.20	6.81 ± 0.43	6.74 ± 0.29	.572	6.75 ± 0.39	6.74 ± 0.40	.922	.742
Albumin (g/dL)	3.50	5.00	4.08 ± 0.4	4.1 ± 0.27	.714	3.95 ± 0.25	3.9 ± 0.35	.515	.372
A/G ratioa	1.20	2.20	1.52 ± 0.28	1.58 ± 0.26	.104	1.46 ± 0.3	1.43 ± 0.34	.491	.049
Alk phos (IU/L)	38.00	126.00	56.33 ± 15.74	56.58 ± 13.53	.828	62.42 ± 14.96	62.58 ± 14.04	.892	.738
Bilirubin (mg/dL)	0.30	1.20	0.82 ± 0.29	0.69 ± 0.23	.068	0.77 ± 0.26	0.78 ± 0.42	.927	.367
Ca Osmol (mOsm/kg)	260.00	300.00	275.17 ± 3.17	274.07 ± 4.19	.355	273.75 ± 4.6	273.91 ± 3.53	.909	.472

The average ± standard deviation is shown.

^aAlbumin/Globulin ratio.

^*P-values for changes from baseline to 2 weeks within each group.

^**P-values for comparing changes between the two groups.

ACE, aqueous cyanophyta extract.