FIG. 1.
FTC reclassification. (A) Distribution of pathologic diagnoses after contemporary review. The majority of cases (n = 47, 71%) were reclassified to diagnoses other than FTC. Nineteen (29%) remained FTC. (B) Distribution of pathologic diagnoses after contemporary review by decade. The proportion of cases reclassified to PTC decreased over time, from 100% (n = 4) in the 1960s to 4% (n = 1) in the 2000s. The proportion of cases reclassified to FA slightly increased over time, from <20% in the 1970s and 1980s to >30% in the 1990s and 2000s. The proportion of cases remaining FTC varied between 0% and 43%. (C) Interobserver variability among three pathologists. Consensus diagnosis (three agreed) was achieved in >60% in all diagnostic categories. Majority consensus (two agreed) was achieved in 20–40% in all categories. Initial lack of consensus occurred in only two cases, in which a majority consensus ultimately revealed FTC. PTC, papillary thyroid carcinoma; PDC, poorly differentiated thyroid carcinoma; FTC, follicular thyroid carcinoma; FA, follicular adenoma.