Table 6.
List of ECM-Related Upregulated Genes in Skeletal Muscles Following Oral PVS Supplementation
| Transcript cluster ID | Gene symbol | Gene description | Fold change | P |
|---|---|---|---|---|
| 19015271 | TNXB | Tenascin XB | 1.78 | .0311 |
| 19011964 | TNXB | Tenascin XB | 1.76 | .0467 |
| 18807632 | TNXB | Tenascin XB | 1.75 | .0425 |
| 19018936 | TNXB | Tenascin XB | 1.74 | .0427 |
| 19012977 | TNXB | Tenascin XB | 1.71 | .0430 |
| 18907606 | DCN | Decorin | 2.23 | .0186 |
| 18907622 | DCN | Decorin | 1.09 | .0338 |
| 18874445 | MYOF | Myoferlin | 1.11 | .0207 |
| 18963453 | COL1A1 | Collagen, type I, alpha1 | 4.61 | .0149 |
| 18811819 | COL1A2 | Collagen, type I, alpha2 | 5.13 | .0076 |
| 18723098 | COL3A1/MIR3606 | Collagen, type III, alpha1/microRNA3606 | 5.18 | .0086 |
| 18735673 | COL5A2 | Collagen, type V, alpha2 | 1.62 | .0324 |
| 18738278 | COL6A3 | Collagen, type VI, alpha3 | 2.96 | .0122 |
| 18830114 | COL14A1 | Collagen, type XIV, alpha1 | 2.07 | .0061 |
| 18810809 | ELN | Elastin | 1.13 | .0187 |
| 18934479 | FBN1 | Fibrillin1 | 3.05 | .0254 |
| 18737057 | FN1 | Fibronectin1 | 3.65 | .0084 |
Data presented indicate fold change in expression of ECM-related genes following 8 weeks of oral PVS supplementation compared with corresponding baseline visits. Data correspond to Figure 1B (P < .05; FDR <5%).
ECM, extracellular matrix.