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Quantification of the Release Kinetics of 14C-HB-IGF-1, 125I-PDGF-BB, and 125I-TGF-β1 from KLD Hydrogels
| Growth factor |
 (days)
|
Release at 4 days | Release at 2 weeks |
|---|---|---|---|
| 14C-HB-IGF-1 | 1.62 | 86% | 95% |
| 125I-PDGF-BB | 3.50 | 58% | 83% |
| 125I-TGF-β1 | 6.20 | 16% | 30% |
The characteristic release time, τ, for each growth factor was determined by fitting a first-order exponential of the form f = a(1-e−bt) to the data shown in Figure 7, where τ = 1/b.
