FIG. 4.

Assessment of cellular populations within ANAs using histology. The area of the axonal front (Fig. 2A) was assessed using histology to identify cellular composition within ANAs. (A) Representative electron micrograph of histological section of 3-cm ANA, where A, myelinated axons; SC, Schwann cell; S, stromal cell; Lk, leukocyte; E, endothelial cell (which were not quantified due to insignificant representation in electron microscopy images). (B) The composition of the total cell population is represented for the percentage of Schwann cells, stromal cells, and leukocytes. Means with standard deviation are represented, n = 4 per group, and # indicates statistical significance to injured nerve (p < 0.05). Color images available online at www.liebertpub.com/tea