TABLE 4.

Sex-Specific Unadjusted and Multivariate-Adjusted HR (95% CIs) for BP as a Continuous Variable for Risk for CVD Mortality, CHD Mortality, and Stroke Mortality

Model	Men (n = 15,868)		Women (n = 11,213)
	SBP, 10 mm Hg	DBP, 5 mm Hg	SBP, 10 mm Hg	DBP, 5 mm Hg
CVD mortality
Model 1 (unadjusted)	1.26 (1.23–1.30)‡	1.25 (1.22–1.28)‡	1.37 (1.31–1.43)‡	1.28 (1.23–1.33)‡
Model 2	1.18 (1.15–1.21)‡	1.15 (1.13–1.18)‡	1.19 (1.13–1.25)‡	1.14 (1.09–1.19)‡
Model 3	1.13 (1.10–1.17)‡	1.12 (1.09–1.15)‡	1.15 (1.09–1.21)‡	1.11 (1.07–1.17)‡
Model 4	1.06 (1.01–1.10)†	1.08 (1.05–1.12)‡	1.10 (1.02–1.19)*	1.05 (0.99–1.12)
CHD mortality
Model 1 (unadjusted)	1.25 (1.20–1.29)‡	1.24 (1.20–1.27)‡	1.41 (1.33–1.49)‡	1.30 (1.24–1.37)‡
Model 2	1.16 (1.12–1.20)‡	1.14 (1.11–1.17)‡	1.23 (1.15–1.31)‡	1.16 (1.10–1.23)‡
Model 3	1.11 (1.07–1.16)‡	1.10 (1.07–1.14)‡	1.17 (1.10–1.25)‡	1.12 (1.06–1.19)‡
Model 4	1.05 (0.997–1.10)	1.08 (1.03–1.12)‡	1.14 (1.03–1.25)†	1.04 (0.96–1.12)
Stroke mortality
Model 1 (unadjusted)	1.39 (1.29–1.51)‡	1.38 (1.29–1.47)‡	1.35 (1.22–1.50)‡	1.27 (1.16–1.39)‡
Model 2	1.29 (1.19–1.40)‡	1.27 (1.19–1.36)‡	1.19 (1.06–1.33)†	1.14 (1.03–1.26)†
Model 3	1.26 (1.16–1.37)‡	1.25 (1.17–1.35)‡	1.19 (1.06–1.34)†	1.14 (1.03–1.26)*
Model 4	1.08 (0.96–1.23)	1.19 (1.07–1.33)†	1.13 (0.95–1.34)	1.06 (0.92–1.22)

Sex-specific unadjusted and adjusted HRs (95% CI) of BP (continuous variable) for risk for CVD mortality, CHD mortality, and stroke mortality are shown. As adjustment factors, model 2 includes demographic variables (age at baseline, race, and education) plus SBP (or DBP), model 3 includes demographic variables plus clinical characteristics (body mass index, current smoking, total cholesterol, and diabetes) plus SBP (or DBP), and model 4 includes demographic variables plus clinical characteristics plus SBP plus DBP. Statistical significance was defined as p < 0.05.

^*p < 0.05;

^†p < 0.01;

^‡p < 0.001.

Abbreviations as in Tables 1 and 3.