Table 2.

Average litter size of control and KO mice (CRISPR/Cas9 system)

	Control				KO
Gene	Genotype	Average litter ± SD	No. of males	No. of litters	Genotype	Average litter ± SD	No. of males	No. of litters	Mating period
1110017D15Rik	WT	8.0 ± 3.0	1	2	−6+2/−6+2	9.2 ± 0.8	3	6	a
1700011E24Rik					−28/−28	10.8 ± 0.5	3	6	a
1700015F17Rik					−2/−2	9.3 ± 1.5	2	12	c
1700019N19Rik					−50/−50	8.6 ± 1.6	3	15	b
2900092C05Rik					+1/+1	10.9 ± 2.2	2	9	c
4930522H14Rik					−7/−7	8.2 ± 2.8	2	13	c
4931406B18Rik	Hetero	12.3 ± 1.0	3	6	+1/+1	10.5 ± 1.0	3	6	a
4933417A18Rik	Hetero	10 ± 1.9	1	9	−4/−4	8.9 ± 2.0	3	8	a
BC051142	Hetero	10 ± 1.4	3	6	−5/−5	8.5 ± 0.3	3	6	a
BC051628	Hetero	9.9 ± 2.5	2	8	−82/−82	8.3 ± 0.8	3	10	a
BC089491					−8/−8	10.2 ± 1.7	3	11	a
C1qtnf4					−40/−40	9.3 ± 1.7	2	11	b
Ccdc178					−7/−7	6.9 ± 2.0	3	17	c
Col20a1					+4/+4	10.1 ± 1.6	2	13	b
Fam217a	Hetero	9.3 ± 1.4	3	6	−4/−4 and −35/−35	9.3 ± 1.7	4	8	a
Fmr1nb					−1/Y	8.1 ± 0.9	3	9	a
Gm5617					−1/−2	10.3 ± 1.1	3	7	a
Kif2b	Hetero	8.8 ± 1.3	2	8	−5/−5	9.8 ± 1.1	3	12	a
Lyzl1					−13/−13	9.0 ± 2.0	3	12	b
March11	Hetero	8.6 ± 3.0	3	14	−50/−50	9.8 ± 2.6	5	9	a
Ms4a13					−5/−5	10.1 ± 1.5	2	7	a
Pinlyp					−7/−7	10.0 ± 2.0	2	5	a
Smim23					−2/−2	9.6 ± 1.2	2	9	c
Spaca7					−4/−4	10.3 ± 2.5	3	14	b
Spink8	Hetero	10.3 ± 2.0	2	6	+1/+1 and +1/−5	10.0 ± 1.9	4	12	a
Tktl1					−11+4/Y	7.4 ± 2.7	3	6	a
Tmco5					+1/+1	9.5 ± 0.7	2	11	b
Tmem247					−13/−13	11.6 ± 0.8	2	10	c
Ube2u					−2+4/−2+4	10.4 ± 1.2	3	11	a
Ubqln3					−1,858/−1,858	11.3 ± 2.0	2	7	a
Ubqlnl	Hetero	10.0 ± 1.4	1	4	+1/+1	10.0 ± 2.0	2	13	b
Control	WT	9.0 ± 1.5	3	15

The mating periods of KO mice were as follows: a, 5–8 wk; b, 9–12 wk; c, 13–16 wk.