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. 2016 Jun 29;113(28):E4079–E4087. doi: 10.1073/pnas.1600982113

Fig. 1.

Fig. 1.

Tumor growth rates in CMG2- and TEM8-null mice. (A) Littermate Cmg2+/+, Cmg2+/−, and Cmg2−/− athymic nude (Foxn1nu/nu) mice were injected intradermally with 1 × 107 per mouse A549 cells. (B and C) Littermate Cmg2+/+, Cmg2+/−, and Cmg2−/− immunocompetent C57BL/6J mice were inoculated with 5 × 105 per mouse LLC cells (B) or 5 × 105 per mouse B16-BL6 cells (C). (D and E) Soft food-fed (body weight-corrected) Tem8−/− mice and their littermate Tem8+/+ immunocompetent C57BL/6J mice were inoculated with 5 × 105 per mouse LLC cells (D) or 5 × 105 per mouse B16-BL6 cells (E). Tumor volumes (mean ± SE) and body weights of the mice (mean ± SD) were monitored. Student’s t test or one-way ANOVA (when ≥3 groups) did not detect significant differences in each panel.