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Glycans on misfolded CPY are accessible for demannosylation. The relative abundance of each glycan on CPYm9 or Scr-CPYm9 after 24-h incubation with Mns1p and/or Htm1p–Pdi1p or E222Q. Shown are the mean values ± one SD from an experiment performed in triplicate. P values were calculated by unpaired t test.
