Table 2. Distribution of loss or intact H3K27me3 according to tumor subtype.
| Loss of H3K27me3 | Intact H3K27me3 | |
|---|---|---|
| MPNSTs | 55 (34%) | 107 (66%) |
| -Triton | 0 (0%) | 5 (100%) |
| -NF1 associated | 33(41%) | 47(59%) |
| -Sporadic | 17(32%) | 37(68%) |
| Neurofibroma | 0 (0%) | 97 (100%) |
| -Atypical | 0 (0%) | 8 (100%) |
| -Plexiform | 0 (0%) | 24 (100%) |
| Schwannoma | 1 (2%) | 43 (98%) |
| Perineurioma | 0 (0%) | 4 (100%) |
| Sarcoma NOS | 0 (0%) | 26 (100%) |
| Undifferentiated pleomorphic or spindle cell sarcoma | 5 (3%) | 172 (97%) |
| Angiosarcoma | 2 (10%) | 19 (90%) |
| Myxofibrosarcoma | 0 (0%) | 17 (100%) |
| Synovial sarcoma | 9 (60%) | 6 (40%) |
| Melanoma | 1 (11%) | 8 (89%) |
| DFSP | 3 (38%) | 5 (62%) |
| Clear cell sarcoma | 2 (40%) | 3 (60%) |
| Leiomyosarcoma | 0 (0%) | 5 (100%) |
| Dedif. Liposarcoma | 0 (0%) | 1 (100%) |
| Pleomorphic liposarcoma | 0 (0%) | 5 (100%) |
| Rhabdomyosarcoma | 0 (0%) | 2 (100%) |
| Osteosarcoma | 1 (50%) | 1 (50%) |
MPNST=malignant peripheral nerve sheath tumor; NOS= not otherwise specified; DFSP=dermatofibrosarcoma protuberans.