. 2016 Jun 11;59(13):6444–6454. doi: 10.1021/acs.jmedchem.6b00628

Table 1. Select MBP Fragments That Displayed Potent Inhibition against Influenza PA Endonuclease³¹^,^a.

pIC₅₀ is defined as pIC₅₀ = −log(IC₅₀) and is included to allow a linear comparison between IC₅₀ values. Ligand efficiency (LE) provides a measure of binding energy per non-hydrogen atom in the fragment molecule.

Table 1. Select MBP Fragments That Displayed Potent Inhibition against Influenza PA Endonuclease31,a.

Table 1. Select MBP Fragments That Displayed Potent Inhibition against Influenza PA Endonuclease³¹^,^a.