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. 2016 Jun 10;7(7):2551–2564. doi: 10.1364/BOE.7.002551

Table 2. K-distribution and OCT parameters in human in vivo tissuesa.

Depth
(µm)
Skin (finger)
Fingernail
αF αV Neff SNR αF αV Neff SNR
(mean ± SD) (mean) (mean) (mean ± SD) (mean) (mean)
90 4.0 ± 1.6 5.1 ± 1.4 2.3 19.3 19.3 ± 5.2 13.1 ± 2.6 8.1 12.8
180 3.3 ± 0.5 2.8 ± 0.5 1.5 13.7 8.7 ± 0.5 9.3 ± 1.8 4.5 11.4
270 4.3 ± 0.9 2.7 ± 0.8 1.8 11.6 3.3 ± 0.9 2.8 ± 0.9 1.5 14.6
a

K-distribution shape parameter α, effective number of scatterers in coherence volume Neff, and SNR of OCT measurements in human skin (finger) and fingernail. For each sample, three measurements were repeated at laterally different sample positions. The shape parameters αF and αV generally agree well, and the SNR > 10 dB, suggesting the suitability of the K-distribution PDF formalism. As seen, the derived effective number of scatterers Neff ( = αave/2) in the OCT coherence volume ranges from ~2 to ~8. The higher SNR at 270 µm for fingernail compared to other depths is indicative of higher reflectance from the deeper bright ventral nail plate as observed in Fig. 6(b); this is not a system-related SNR anomaly, since the measured sensitivity had a monotonic roll-off (~10dB/mm), without singularities over the whole depth range.