Table 4.
Posterior Mean and Variance |
Correlations |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameter | Description | Mean | Variance | α | PB | dS | pL | qM | qS | |||
α | Baseline mortality (logit scale) | −1.07 | 0.11 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of albumin on mortality | −0.31 | 0.51 | 0 | 1 | 0.64 | 0.44 | 0 | 0.25 | 0 | 0 | 0 | |
Effect of saline on mortality | −2.34 | 0.64 | 0 | 0.64 | 1 | 0.51 | 0 | 0.27 | 0 | 0 | 0 | |
Effect of gelofusine on mortality | −0.19 | 1.81 | 0 | 0.44 | 0.51 | 1 | 0 | 0.27 | 0 | 0 | 0 | |
PB | Baseline NS | 0.10 | 0.04 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
dS | Change to NS risk in “saved” patients | 1.88 | 4.52 | 0 | 0.25 | 0.27 | 0.27 | 0 | 1 | 0 | 0 | 0 |
pL | Probability that short-term NS proves permanent | 0.50 | 0.08 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
qM | QALYs gained by those who survive and are NS-free | 19.99 | 24.97 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
qS | QALY loss from NS | 5.38 | 7.94 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Note: MCMC = Markov chain Monte Carlo; NS = neurological sequelae; QALY = quality-adjusted life-year.