Table 2. Biodistribution of 111In-CP04 in healthy Swiss albino mice.
%ID/g tissue ± SD (n = 4) |
||||||
---|---|---|---|---|---|---|
111In-CP04 |
||||||
Organs | 30 min | 1h | 4h | 24 h | 48 h | 72 h |
Blood | 1.74 ± 0.22 | 0.51 ± 0.14 | 0.02 ± 0.01 | 0.00 ± 0.00 | 0.01 ± 0.01 | 0.01 ± 0.01 |
Liver | 0.77 ± 0.11 | 0.32 ± 0.15 | 0.12 ± 0.02 | 0.06 ± 0.01 | 0.06 ± 0.00 | 0.05 ± 0.01 |
Heart | 0.70 ± 0.10 | 0.21 ± 0.04 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.03 ± 0.02 |
Kidneys | 9.80 ± 2.07 | 8.84 ± 2.05 | 7.90 ± 1.98 | 3.61 ± 0.31 | 2.81 ± 0.63 | 2.62 ± 0.24 |
Stomach | 4.88 ± 0.85 | 2.99 ± 0.55 | 2.61 ± 0.82 | 1.48 ± 0.55 | 1.26 ± 0.26 | 0.92 ± 0.04 |
Intestines | 0.82 ± 0.14 | 0.39 ± 0.12 | 1.05 ± 0.35 | 0.18 ± 0.14 | 0.08 ± 0.02 | 0.09 ± 0.04 |
Spleen | 0.36 ± 0.04 | 0.14 ± 0.04 | 0.05 ± 0.01 | 0.04 ± 0.01 | 0.03 ± 0.01 | 0.04 ± 0.01 |
Muscle | 0.59 ± 0.10 | 0.18 ± 0.04 | 0.04 ± 0.02 | 0.02 ± 0.01 | 0.03 ± 0.02 | 0.03 ± 0.02 |
Lung | 1.05 ± 0.10 | 0.40 ± 0.10 | 0.06 ± 0.01 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.03 ± 0.01 |
Femur | 4.62 ± 1.24 | 2.62 ± 0.42 | 0.96 ± 0.18 | 0.53 ± 0.04 | 0.55 ± 0.11 | 0.49 ± 0.06 |
Pancreas | 0.67 ± 0.08 | 0.26 ± 0.08 | 0.10 ± 0.01 | 0.05 ± 0.01 | 0.04 ± 0.01 | 0.06 ± 0.03 |