Table 5. Expected absorbed doses of 111In-CP04 in humans based on two scaling models for translating mouse to human data.
| Absorbed dose per injected activity (mGy/MBq) |
||
|---|---|---|
| Organs | Option 1 | Option 2 |
| LLI wall | 0.078 | 0.075 |
| Small intestine | 0.026 | 0.024 |
| Stomach wall | 0.012 | 0.011 |
| ULI wall | 0.037 | 0.035 |
| Heart wall | 0.005 | 0.003 |
| Kidneys | 0.039 | 0.124 |
| Liver | 0.005 | 0.009 |
| Lungs | 0.004 | 0.003 |
| Muscle | 0.010 | 0.009 |
| Pancreas | 0.008 | 0.017 |
| Red marrow | 0.010 | 0.012 |
| Osteogenic cells | 0.015 | 0.034 |
| Spleen | 0.007 | 0.011 |
| Urinary bladder wall | 0.459 | 0.456 |
| Total body | 0.011 | 0.010 |
| Effective dose (mSv/MBq) | 0.045 | 0.044 |