Table S1.
Comparison of baseline characteristics of the brain surgery cohort and SRS cohort
| Characteristic | Brain surgery (n=22) | SRS (n=54) | P-value |
|---|---|---|---|
| Median age, years (range) | 55 (34–71) | 61 (30–82) | 0.465 |
| Sex, n (%) | |||
| Male | 18 (81.8%) | 34 (63.0%) | 0.102 |
| Female | 4 (18.2%) | 20 (37.0%) | |
| Smoking status, n (%) | |||
| Smoker | 16 (72.7%) | 31 (57.4%) | 0.212 |
| Never-smoker | 6 (33.7%) | 23 (42.6%) | |
| Histology, n (%) | |||
| Adeno | 21 (95.5%) | 36 (66.7%) | 0.082 |
| SCC | 0 (0.0%) | 9 (16.7%) | |
| Others | 1 (4.5%) | 9 (16.7%) | |
| Stage, n (%) | |||
| IA | 0 (0.0%) | 0 (0.0%) | 0.123 |
| IB | 1 (4.5%) | 0 (0.0%) | |
| IIA | 5 (22.7%) | 9 (16.7%) | |
| IIB | 3 (13.6%) | 8 (14.8%) | |
| IIIA | 12 (54.5%) | 37 (68.5%) | |
| Number of brain metastasis, n (%) | |||
| 1 | 16 (72.7%) | 32 (59.3%) | 0.098 |
| 2 | 5 (22.7%) | 14 (25.9%) | |
| 3 | 1 (4.5%) | 8 (14.8%) | |
| Size of largest lesion, mm (range) | 31 (8–60) | 15 (7–30) | 0.003 |
| WBRT or not | |||
| Yes | 21 (95.5%) | 4 (7.4%) | <0.001 |
| No | 1 (4.5%) | 50 (92.6%) | |
| Thoracic therapy, n (%) | |||
| Surgery | 10 (45.5%) | 11 (20.4%) | 0.027 |
| No surgery | 12 (54.5%) | 43 (79.6%) | |
Abbreviations: SRS, stereotactic radiosurgery; SCC, squamous cell carcinoma; WBRT, whole-brain radiation therapy.