Table S2.
Comparison of baseline characteristics of thoracic surgery cohort and no thoracic surgery cohort
| Characteristic | Thoracic surgery (n=21) | No thoracic surgery (n=55) | P-value |
|---|---|---|---|
| Median age, years (range) | 50 (41–74) | 63 (30–82) | 0.018 |
| Sex, n (%) | |||
| Male | 15 (71.4%) | 37 (67.3%) | 0.449 |
| Female | 6 (28.6%) | 18 (32.7%) | |
| Smoking status, n (%) | |||
| Smoker | 13 (61.9%) | 34 (61.8%) | 0.994 |
| Never-smoker | 8 (38.1%) | 21 (38.2%) | |
| Histology, n (%) | |||
| Adeno | 17 (81.0%) | 40 (72.7%) | 0.058 |
| SCC | 1 (4.8%) | 8 (14.5%) | |
| Others | 3 (14.3%) | 7 (12.7%) | |
| Stage, n (%) | |||
| IA | 0 (0.0%) | 0 (0.0%) | 0.120 |
| IB | 1 (4.8%) | 0 (0.0%) | |
| IIA | 6 (28.6%) | 9 (16.4%) | |
| IIB | 4 (19.0%) | 7 (12.7%) | |
| IIIA | 10 (47.6%) | 39 (70.9%) | |
| Number of brain metastasis, n (%) | |||
| 1 | 16 (76.2%) | 32 (58.2%) | 0.081 |
| 2 | 5 (23.8%) | 14 (25.5%) | |
| 3 | 0 (0.0%) | 9 (16.4%) | |
| Size of largest lesion, mm (range) | 15 (7–42) | 19 (7–60) | 0.012 |
| Brain therapy, n (%) | |||
| Surgery + WBRT | 10 (47.6%) | 11 (20.0%) | 0.121 |
| Surgery only | 0 (0.0%) | 1 (1.8%) | |
| SRS + WBRT | 0 (0.0%) | 4 (7.3%) | |
| SRS only | 11 (52.4%) | 39 (70.9%) | |
Abbreviations: SCC, squamous cell carcinoma; WBRT, whole-brain radiation therapy; SRS, stereotactic radiosurgery.