Table 1. Cellular processes in the airway epithelium model.
Qk | Process | Δk i1 | Δk i2 | Δk i3 |
---|---|---|---|---|
Q1 | Differentiation of SCs into SecrCs by symmetric divisions | -1 | 2 | 0 |
Q2 | Differentiation of SCs into CilCs by symmetric divisions | -1 | 0 | 2 |
Q3 | Symmetric self-renewal of SCs | 1 | 0 | 0 |
Q4 | Differentiation of SecrCs into CilCs by symmetric divisions | 0 | -1 | 2 |
Q5 | Symmetric self-renewal of SecrCs | 0 | 1 | 0 |
Q6 | De-differentiation of SecrCs | 1 | -1 | 0 |
Q7 | Death of SecrCs | 0 | -1 | 0 |
Q8 | Death of CilCs | 0 | 0 | -1 |
Q9 | Asymmetric divisions of SCs producing one SecrC offspring | 0 | 1 | 0 |
Q10 | Asymmetric divisions of SCs producing one CilC offspring | 0 | 0 | 1 |
Q11 | Asymmetric divisions of SecrCs producing one CilC offspring | 0 | 0 | 1 |
A description of the processes depicted in Fig 1. Although processes Q5 and Q9, Q10 and Q11 are equivalent from the viewpoint of cellular population change, we count them as different processes, because they can be regulated differently.