Table 2. Summary of down-regulated microRNAs and their up-regulated targets in drinkers.
miRNA down-regulated in heavy drinkers | Fold Change | Gene targets up-regulated in heavy drinkers |
---|---|---|
miR-23a | 6.7 | PTP4A2, CA2, NCKAP1, XRCC2, GRTP1, MAP1B |
miR-24 | 7.2 | NEFM, BNIP3L, STRADB, EHD2, WWRT1, XRCC2, AMOTL2, FKBP1B, HBQ1, C6orf25, GSTO2 |
miR-27a | 6.2 | PAQR9, NR2F6, RGS2, RNF152, AMOTL2, GATA2, MAP1B |
miR-663 | 18.7 | MYL9, NRGN, CCTN |