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. 2016 Jul 18;11(7):e0159508. doi: 10.1371/journal.pone.0159508

Fig 3. An Ala residue at the MAPK site neutralizes the reduced eye of M8-S159D, but permits bristle suppression.

Fig 3

(A) Scanning EM of the adult eye at 200x magnification. The CK2 mimic with an Ala at the MAPK site (M8-S151A+S159D) fails to elicit a reduced eye upon expression at stage-2/3 of the MF. The facet counts (inset) are equivalent to those in wild type flies (not shown). Note that M8-S151A+S159D elicits loss of many IOBs (dashed oval). (B, C) Nota of flies of the indicated genotypes exhibiting loss of MCs. Inset in panels B and C denote MCs remaining per heminotum. (D) The MAPK mimic (M8-S151D) and the dual-kinase mimic (M8-S151D+S159D) elicit embryonic lethality (EL) upon expression with scaGal4 at either 24°C or 18°C, reflecting expression in most PNCs.