Table 1. Results of the meta-analysis on prognostic significance of NLR in CRLM.
Overall Survival | Recurrence Free Survival | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
No. studies | No. patients | HR | 95% CI | I2,% | P value for heterogeneity | No. studies | No. patients | HR | 95% CI | I2,% | P value for heterogeneity | |
Overall | 7 | 1491 | 2.17 | 1.82–2.58 | 0 | 0.66 | 6 | 1093 | 1.96 | 1.64–2.35 | 45.20 | 0.10 |
Treatment methods | ||||||||||||
Surgical resection | 5 | 1309 | 2.08 | 1.73–2.49 | 0 | 0.74 | 4 | 903 | 1.89 | 1.34–2.66 | 58.60 | 0.07 |
Non-surgical treatment | 2 | 182 | 3.11 | 1.83–5.29 | 0 | 0.71 | 2 | 190 | 2.33 | 1.37–3.95 | 29.90 | 0.23 |
Sample size | ||||||||||||
≥100 | 5 | 1309 | 2.08 | 1.73–2.49 | 0 | 0.74 | 3 | 286 | 1.79 | 1.24–2.59 | 68.20 | 0.04 |
<100 | 2 | 182 | 3.11 | 1.83–5.29 | 0 | 0.71 | 3 | 807 | 2.48 | 1.55–3.98 | 0 | 0.42 |
NLR cutoff | ||||||||||||
= 5 | 6 | 1322 | 2.17 | 1.81–2.60 | 0 | 0.53 | 4 | 826 | 2.27 | 1.84–2.80 | 0 | 0.69 |
= 2.5 | 1 | - | - | - | - | - | 2 | 267 | 1.30 | 0.91–1.85 | 0 | 0.46 |
NLR: neutrophil-lymphocyte ratio; HR: hazard ratio; CI: confidence interval.