Fig 1. Genetic arrangement in the Spn556II locus.
A. The three functional DNA methylation motifs recognized by the three R-M systems in strain ST556 according to our previous study [35]. The methylated bases are highlighted with red characters. B. The gene order and other features in the Spn556 locus of three pneumococcal strains. The orientations of the coding sequences are indicated by arrowheads. Each hsdS segment with identical or nearly identical sequences between the two of three strains (ST556, TIGR4 and D39) is indicated with a dashed line. Drawing is not to scale.