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. 2016 Jul 18;12(7):e1005762. doi: 10.1371/journal.ppat.1005762

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© 2016 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — DNA configurations derived by three inversions from form S1 (A), S3 (B), or S4 (C). Each gene and its orientation are indicated with a large arrow. The inverted repeats (IRs) in the hsdS genes are represented by yellow (IR1), black (IR2), and white (IR3) arrowheads. The inversion sites are indicated by dashed lines. Each DNA configuration is assigned with an S number. DNA configurations generated by excisions between hsdS _A and hsdS _C demarcated by direct repeat sets 1 (DR1, red arrows) and (DR2, purple arrows) (D). Excisions mediated by the DR1 and DR2 yields hsdS _A variant S9 and S7. Further inversion in S7 generates S8. S7 may also generate variant S9 by further DNA excision between DR1.1 and DR1.2.