Table 1. Sample characteristics by subclinical disease in the Jackson Heart Study.
Total | LVH (n=3114) | PAD (n=4026) | CAC (n=2661) | CIMTa (n=4524) | ||||||||
N=4766(%) | No | Yes | P | No | Yes | P | None | Any | P | mean(SD) | P | |
Women | 3059(64%) | 1839(64%) | 155(70%) | .05 | 2420(64%) | 155(68%) | .193 | 1010(69%) | 731(61%) | <.001 | .70(.17) | <.001 |
Men | 1697(36%) | 1054(36%) | 66(30%) | 1378(36%) | 73(32%) | .193 | 449(31%) | 471(39%) | .75(.2) | |||
Age (mean) | 53.93(12.78) | 51.08(12.44) | 58.95(10.86) | <.001 | 53.41(12.31) | 61.34(13.85) | <.001 | 50.03(9.64) | 59.39(10.05) | <.001 | ||
Current smoker | 594(13%) | 340(12%) | 37(17%) | .022 | 456(12%) | 40(18%) | <.001 | 108(7%) | 156(13%) | <.001 | .72(.17) | <.001 |
Alcohol drinking per week | 3.50(7.65) | 3.30(7.32) | 1.69(2.98) | .057 | 3.65(7.88) | 3.44(10.23) | .815 | 2.91(7.71) | 3.50(7.04) | .176 | ||
Total physical activity score | 8.48(2.57) | 8.81(2.49) | 7.64(2.54) | <.001 | 8.63(2.52) | 7.16(2.47) | <.001 | 9.05(2.35) | 8.17(2.54) | <.001 | ||
% Calories from fat | 35.16(6.90) | 35.42(6.86) | 34.28(7.84) | .020 | 35.20(6.90) | 34.54(6.98) | .175 | 36.15(6.53) | 34.80(7.08) | <.001 | ||
BMI (mean) | 31.77(7.29) | 30.98(6.73) | 36.14(8.20) | <.001 | 31.46(6.84) | 29.76(6.87) | <.001 | 31.28(6.59) | 31.57(6.42) | .260 | ||
<18.5 | 22(0%) | 10(0%) | 1(0%) | <.001 | 15(0%) | 3(1%) | <.001 | 4(0%) | 6(0%) | .132 | .67(.13) | <.001 |
18.5-24.9 | 674(14%) | 459(16%) | 12(5%) | 546(14%) | 49(21%) | 212(15%) | 140(12%) | .7(.17) | ||||
25-29.9 | 1525(32%) | 999(34%) | 43(19%) | 1249(33%) | 82(36%) | 495(34%) | 416(35%) | .73(.19) | ||||
≥30 | 2547(53%) | 1429(49%) | 165(75%) | 1988(52%) | 94(41%) | 748(51%) | 640(53%) | .72(.18) | ||||
Hypertension | 2815(60%) | 1503(52%) | 190(86%) | <.001 | 2184(58%) | 169(74%) | <.001 | 706(49%) | 865(73%) | <.001 | .76(.19) | <.001 |
Type 2 diabetes | 782(17%) | 384(14%) | 65(31%) | <.001 | 572(15%) | 59(26%) | <.001 | 123(9%) | 256(22%) | <.001 | .79(.21) | <.001 |
Hypercholesterolemia | 1337(31%) | 743(28%) | 76(39%) | .001 | 1060(30%) | 104(50%) | <.001 | 313(23%) | 463(42%) | <.001 | .76(.18) | <.001 |
Hypertriglyceridemia | 288(7%) | 155(6%) | 7(4%) | .233 | 233(7%) | 14(7%) | .902 | 46(4%) | 97(10%) | <.001 | .74(.19) | .004 |
Values in the table represent N (%) for categorical variables and mean (SD) otherwise; P for unadjusted differences are from Pearson’s chi-squared tests for categorical variables and t-tests for continuous variables.
SEP, socioeconomic position; LVH, left ventricular hypertrophy; PAD, peripheral arterial disease; CAC, coronary artery calcification; CIMT, carotid intima media thickness; SD, standard deviation; BMI, body mass index.
Characteristics and CVD risk factor data by subclinical disease from the 5,301 participants enrolled in the Jackson Heart Study.
a. µm.