Fig 6. Measured IHA titers (A) and protein-array–derived average signal intensities (B) per serum.

Melioidosis-positive and -negative samples were drawn in endemic areas of Thailand. Additionally, means with standard error of the mean (SEM) are shown for each group. The IHA titer was determined using the indirect hemagglutionation assay described elsewhere (http://www.melioidosis.info/home.aspx). Statistical analyses were performed using the Kruskal-Wallis test followed by Dunn's Multiple Comparison test, comparing titers or signal intensities measured in sera of weeks 0 (n = 75), 12 (n = 50), and 52 (n = 46), as well as from healthy individuals (n = 100) (*p<0.05; **p<0.01; ***p<0.001).