Table 1. GTP and RNA cap analog competition analysis with CHIKV nsP1.
| GTP Analog | Average Ki | Standard Error | Fold Change |
|---|---|---|---|
| XTP | 4.02E-07 | 3.20E-08 | 0.74 |
| ddGTP | 4.25E-07 | 4.68E-09 | 0.78 |
| GTP | 5.46E-07 | 2.19E-09 | 1 |
| me7-GTP | 1.55E-06 | 2.32E-07 | 2.84 |
| GpppA | 1.89E-06 | 3.81E-07 | 3.46 |
| ITP | 1.91E-06 | 2.11E-08 | 3.50 |
| ATP | 3.34E-06 | 2.78E-07 | 6.12 |
| dGTP | 4.21E-06 | 8.75E-08 | 7.71 |
| UTP | 4.46E-06 | 1.90E-07 | 8.17 |
| GDP | 4.89E-06 | 8.59E-07 | 8.96 |
| CTP | 6.94E-06 | 9.94E-07 | 12.71 |
| me7-GpppA | 7.00E-06 | 1.15E-06 | 12.82 |
| me7-GMP | 2.19E-05 | 4.42E-06 | 40.11 |
| GMP | 1.33E-04 | 5.08E-09 | 243.59 |
| Guanosine | NA | NA | NA |