Skip to main content
. 2016 Jul 18;12(7):e1005007. doi: 10.1371/journal.pcbi.1005007

Fig 2. Reaction scheme.

Fig 2

Processes are numbered 1–26. Reactions 1–10 represent steps of Wnt/β-catenin signaling involved in active β-catenin regulation in the absence of Wnt3a. Reactions 11–19 represent regulation of Wnt3a binding by both genetic regulation of DPAGT1 and N-glycosylation. Reactions 20–26 represent E-cadherin dynamics and AJ formation. Abbreviations: APC, adenomatous polyposis coli; β-cat, β-catenin; E-cad, E-cadherin; ER, endoplasmic reticulum; ERC, endocytic recycling compartment; GSK3, glycogen synthase kinase 3β; LRP, lipoprotein receptor-related proteins; M, membrane; TCF, T-cell factor. Image partly adapted from [41].